In this research, antimycobacterial activity of the extract of the root and fruit of ferula gummosa was investigated and was tested against mycobacterium bovis. This is antispasmodic, carminative, expectorant and stimulant. Phytochemical constituents, antioxidant activity and toxicity potential. Greenwich academic literature archive ferula gummosa. Antimicrobial and cytotoxic activity of ferula gummosa plant. In food and beverages, galbanum oil and resin are used as flavoring. It is used internally in the treatment of chronic bronchitis, asthma and other chest. Tested at 4% dilution on 25 volunteers it was neither irritating nor sensitizing.
Author links open overlay panel elahe kamelnia a adeleh divsalar b majid darroudi c d. Request pdf ferula gummosa, a traditional medicine with novel applications ferula gummosa with the persian name of barijeh is reputed due to its. Cellulose nanocrystals cncs have recently gained an increasing interest in nanomedicine. Author links open overlay panel fereshteh eftekhar morteza yousefzadi k. Mortality % of echinococcus granulosus protoscoleces over different times of exposure to pelargonium roseum and ferula gummosa essential oils, and their pure major constituents. Ferula species are reputed in folk medicine for the treatment of a variety of disorders. Asa is a latinized form of farsi asa resin, and latin foetidus means smelling, fetid. Abstractferula gummosa with the persian name of barijeh is reputed due to its traditional history.
Sep 17, 2019 galbanum is a gumlike material resin from the roots and trunk of a tree. Cytotoxic activities of phytochemicals from ferula species. Pdf synergistic effects of ferula gummosa and radiotherapy. The plants were identified in shahid beheshti university herbarium in tehran and are kept under voucher specimen number f2959. Liposomes were produced with specific ratios of lecithincholesterol by thinfilm hydration and sonication. Embryogenic culture and karyological changes article pdf available in pakistan journal of biological sciences 1012. Ferula gummosa is an endemic species of the persian mountains.
To this end, the chemical compositions of ferula gummosa essential. Ferula gummosa, a traditional medicine with novel applications. Asafoetida, the gum resin prized as a condiment in india and iran, is obtained chiefly from plant ferula asafoetida. Ferula from latin ferula rod is a genus of about species of flowering plants in the carrot familynative to the mediterranean region east to central asiamostly growing in arid climates. In iranian traditional medicine, an oleogumresin obtain from f. This herbaceous plant of the highdesert regions reproduces only by seed. Ferula from latin ferula, rod is a genus of about 170 species of flowering plants in the family apiaceae, native to the mediterranean region east to central asia, mostly growing in arid climates. Its resin, referred to in the book of exodus as galbanum, has antispasmodic, carminative, expectorant and stimulant properties. Galbanum is sometimes applied directly to the skin for wounds. To learn more about galbanum essential oil, the benefits and how to use it click here. Usda, ars, germplasm resources information network.
A new sesquiterpene coumarin, gumosin 1, two new sesquiterpene coumarin glycosides, gumosides a 2 and b 3, and 10 known compounds, namely, cauferoside 4, feselol 5, conferoside, ferilin, ferocaulidin, ligupersin a, conferol, and daucosterol, and the phenolic compounds acantrifoside e and 4hydroxybenzoic acid 46osulfoglucopyranoside, were isolated from a methanolic extract of. It is also useful as an aid for troubled or mature skin. Mining ferula gummosa transcriptome to identify mirnas. The antimicrobial activity of the oil was tested on three strains of gram positive bacteria staphylococcus aureus, s. The first report of polycarpic genotype in galbanum ferula gummosa boiss. Ferula gummosa with the persian name of barijeh is reputed due to its traditional history. However, it is not a legal authority for statutory or regulatory purposes.
Dehpour 4 antioxidant activity of hydroalcholic extract of ferula gummosa boiss roots. The objective of this study was to evaluate the antiproliferative activities of the seed and gum extracts of f. Antioxidant activity of hydroalcholic extract of ferula. Abstractferula gummosa with the persian name of barijeh is reputed. It is found in mediterranean and east african woodlands and shrublands. Hosted by the usgs core science analytics and synthesis. Comparative morphology and fruit anatomy of ferula szowitsiana. Jun 14, 2018 ferula foetida the active oleoresin being called ferula asafoetida is a supplement catered towards lung and gastrointestinal health, and is used as a carminative agent. Pdf the antimycobacterial activity of the extract of. The usage of medicinal plants as natural antimicrobial agents has grown in many fields including dental medicine.
Present study is planned to show the antibacterial effect of this herb on bacteria isolated from infectious diarrhea. While every effort has been made to provide the most reliable and uptodate information available, ultimate legal requirements with respect to species are contained in. These metrics are regularly updated to reflect usage leading up to the last few days. Hopewell essential oil galbanum essential oil digestion. The genus ferula apiaceae family comprises of more than 3 different species distributed throughout central asia and the mediterranean region. Sesquiterpene coumarins from ferula gumosa journal of. May 23, 20 ferula species are reputed in folk medicine for the treatment of a variety of disorders. Galbanum essential oil is an ancient spiritual oil that has been used for mediation and to increase awareness. The leaves are tripinnate or even more finely divided, with a stout basal sheath clasping. Ferula gummosa is a perennial growing to 1 m 3ft 3in by 1 m 3ft 3in. Ferula galbaniflua and ferula rubricaulis, galbanium.
The antimycobacterial activity of the extract of ferula. We tested the hypothesis that seeds of the monocarpic perennial ferula gummosa from the mediterranean area and central asia. In the search for new natural compounds with acetylcholinesterase ache inhibitory activity this study focused on galbanum, the oleo gum. Galbanum is an aromatic gum resin and a product of certain umbelliferous persian plant species in the genus ferula, chiefly ferula gummosa synonym f. The whole plant, but especially the root, contains the gum resin galbanum.
Antioxidant activity of hydroalcholic extract of ferula gummosa boiss roots. Download fulltext pdf download fulltext pdf the antimycobacterial activity of the extract of ferula gummosa article pdf available in international journal of mycobacteriology 45 january. Galbanumyielding plants grow plentifully on the slopes of the mountain ranges of northern iran. We determined the water permeability of seeds, embryo morphology, temperature requirements for embryo growth and seed germination and responses of seeds to warm and cold stratification and to different. Production of new cellulose nanocrystals from ferula gummosa and their use in medical applications via investigation of their biodistribution. Galbanum essential oil is pale yellow to yellowish brown clear liquid that is extracted through steam distillation from resin ducts of the plant. There have been sporadic reports on the chemopreventive and chemosensitizing activities of some terpenoid coumarin derivatives from the genus ferula. Itis taxonomy is based on the latest scientific consensus available, and is provided as a general reference source for interested parties. The sesquiterpenic composition of the essential oil of iranian oleogumresin ferula gummosa boiss was studied by comprehensive twodimensional gas.
Page designed through the cooperative efforts of interagency itis teams. Our results demonstrated that the ethanolic extract had the lowest. Galbanum is a large perennial herb having smooth stem shiny leaflets with small flowers. Effect of ferula gummosa ethanolic extract on osteogenesis in. Antimicrobial and cytotoxic activity of ferula gummosa. It occurs usually in hard or soft, irregular, more or less translucent and shining lumps, or occasionally in. This page was last edited on 21 december 2019, at 20. Deep and intermediate complex morphophysiological dormancy in. Diffuse or directly inhale best when blended with other oils internal. Preparation of barije ferula gummosa essential oil. It contains resin ducts that exude a milky juice, a natural oleoresin.
The present study examined the cytotoxic effects on hela cells from the induction of apoptosis and radiation sensitivity by ferula gummosa. It may also have benefits to cognition and usage as an aphrodisiac. Mar 01, 2018 ferula gummosa is known for the exudation of galbanum, an invaluable oleogumresin, that is composed of two important parts including terpenes and gums najafabadi et al. The antimicrobial activity of ferula gummosa on bacterial.
People take galbanum for digestion problems, intestinal gas, poor appetite, cough, and spasms. Dilute with a carrier oil and apply on area of concern or as desired. The present study investigated the cytotoxic activity of 11 phytochemicals conferone, farnesiferol a, acantrifoside e, mogoltadone, diversin. An endemic plant in iran, ferula gummosa or galbaniflua is the only true source of soft galbanum. Ferula gummosa in the germplasm resources information network grin, u. Extracts of the plant were achieved using maceration method. The extract of the fruit was achieved by using the maceration method, and the effect of different concentrations of the extract on the growth of mycobacterium was compared with the standard 1 mc farland. Ferula gummosa essential oil how is ferula gummosa essential oil abbreviated. The aim of this study was to load liposomes with barije ferula gummosa essential oil eo and to evaluate their physical and antibacterial properties.
Ferula gummosa grows as a native plant in different parts of iran and has been used for treatment of some infections such as uti since ancient times. Ferula assafoetida, ferula rubricaulis and ferula foetida furnish asafetida. All structured data from the file and property namespaces is available under the creative commons cc0 license. Galbanum is suitable for internal use within safe parameters if such use is deemed appropriate. Download hires image download to mspowerpoint cite this. Ferula definition of ferula by the free dictionary. The antimycobacterial activity of the extract of ferula gummosa. We feel that internal use is rarely needed and should only be. The present study investigated the cytotoxic activity of 11 phytochemicals conferone, farnesiferol a, acantrifoside e, mogoltadone, diversin, galbanic acid. Ferula gummosa compared to the control induced a subg1 peak in the flow cytometry histogram of treated cells thus indicating that apoptotic cell death is involved in ferula gummosainduced toxicity. Ache inhibitory activity this study focused on galbanum, the oleo gum. Among them, more than 30 species are founded in iranian flora of which 15 genuses, including ferula gummosa, are endemic. Deep and intermediate complex morphophysiological dormancy.
It is primarily used in the treatment of spasmodic conditions of the respiratory and digestive systems. Production of new cellulose nanocrystals from ferula. The species is hermaphrodite has both male and female organs and is pollinated by flies. Many other species of ferula genus also produce gums, but of greatly varying qualities. Antibacterial activity of ferula gummosa essential oil was studied against bacterial laboratory atcc standards using the disk diffusion method. Ethanolic extract of ferula gummosa is cytotoxic against.
Department of agriculture agricultural research service. Assessment of the sesquiterpenic profile of ferula gummosa oleo. Ferula gummosa galbanum has been used in traditional medicine since ancient time. They are herbaceous perennial plants growing to 14 m tall, with stout, hollow, somewhat succulent stems. Antibacterial activity of the essential oil from ferula gummosa seed. Author links open overlay panel ahmad sobhani najafabadi a mohammad reza naghavi b. Production of new cellulose nanocrystals from ferula gummosa. Galbanum is sometimes applied directly to the skin for wounds in food and beverages, galbanum oil and resin are used as flavoring in manufacturing, galbanum oil and resin are used as. Invitro activity of ferula gummosa essential oil and its different. It is in flower from may to june, and the seeds ripen from june to august.
Galbanum is exceptionally aromatic, so it is recommended to use sparingly perhaps 1 drop per ounce. Preparation of barije ferula gummosa essential oilloaded. Ferula gummosa boiss apiaceae is an extremely precious medicinal plant which naturally grows throughout the mediterranean and central asia. Ferula gummosa boiss barije in persian, from the family apiaceae, f. Ferula communis, the giant fennel, is a species of flowering plant in the carrot family apiaceae. Terpenes are the most important part of the olegumresin for both industrial and pharmaceutical purposes paduch et al. View enhanced pdf access article on wiley online library html view download pdf for offline viewing. Umbelliferae is a popular medicinal plant, which is known mostly for therapeutic uses of its oleogumresin. Ferula gummosa essential oil how is ferula gummosa. We tested the hypothesis that seeds of the monocarpic perennial ferula gummosa from the mediterranean area and central asia have deep complex morphophysiological dormancy. Ferula gummosa apiaceae antimicrobial essential oil gcms. The production of cncs from ferula gummosa fg by acid hydrolysis are a potential source for nanomedical applications. It was also shown it can sensitize cells to radiationinduced toxicity and apoptosis.
Files are available under licenses specified on their description page. Ferula foetida the active oleoresin being called ferula asafoetida is a supplement catered towards lung and gastrointestinal health, and is used as a carminative agent. Mining ferula gummosa transcriptome to identify mirnas involved in the regulation and biosynthesis of terpenes. Ferula asafoetida supplement health benefits, dosage. The isolation of bioactive compounds from plant extracts usually is laborious and time consuming. Greenwich academic literature archive ferula gummosa boiss. Ferula asafoetida supplement health benefits, dosage, side. Antibacterial activity of the essential oil from ferula. Antiepileptic potential and composition of the fruit essential oil of. Synonymic checklists of the vascular plants of the world version mar. Galbanum is a gumlike material resin from the roots and trunk of a tree. It is somewhat related to common fennel, which belongs to another genus, foeniculum, also in the family apiaceae.
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